Botiss cerabone - Mastering protection

Botiss cerabone® is one of the most commonly used bovine bone grafting materials in regenerative dental medicine. It is a dimensionally stable bone graft offering lifetime volume stability.

The unique 1200°C manufacturing process of cerabone removes all organic components for maximum safety and by utilising heat and water only, leads to a 100% pure natural bone mineral (free of chemical additives). Due to its exceptional high purity, cerabone provides dependable volume stability of the augmented site, which is particularly advantageous for support of the soft tissue in the aesthetic region, for preservation of the ridge shape and to protect autologous or allogenic bone from resorption.

The human-like bone structure of cerabone, with its three-dimensional pore-network and bioactive surface result in excellent osteoconductive properties. It promotes the adhesion and invasion of bone forming cells resulting in complete integration of the granules into newly formed bone matrix.

The interconnected pores and superior hydrophilic surface of cerabone support the adhesion of proteins from the blood. cerabone binds and gradually releases signalling molecules thereby providing a long-term depot-effect. In addition, the 100% pure natural bone mineral acts as a calcium reservoir slowly releasing calcium ions important for bone remodelling. The long-term success of cerabone in regenerative dentistry has been proven with more than one million patients treated worldwide over 15 years in various medical applications. Because of its long-term stability, cerabone may be specifically preferred in patients with less adequate bone quality.